Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916537 | 0.83 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2SMN1; SMN2CYP2C19 | |
| SCHEMBL7089238 | 0.83 | — | — | |
| SCHEMBL8326130 | 0.83 | — | — | |
| SCHEMBL4355761 | 0.80 | CAD (0.33) | TAS1R3TAS1R1TAS1R2HRH3HRH4 | |
| SCHEMBL8180510 | 0.78 | KMT2A (0.33) | POLBKMT2A | |
| SCHEMBL29066700 | 0.77 | BLM (0.44) | CYP1A2 | |
| SCHEMBL8464768 | 0.77 | MEN1 (0.43) | KMT2A | |
| SCHEMBL8465369 | 0.77 | MEN1 (0.32) | KMT2A | |
| SCHEMBL8959221 | 0.77 | TDP1 (0.33) | KMT2A | |
| SCHEMBL21930790 | 0.75 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673954-B1 | REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST | GENERAL ELECTRIC COMPANY | 2004-01-06 | — | — | US | disclosed |