SCHEMBL6537070

SCHEMBL6537070

O=C(C1=CCC(Oc2cccc(C(=O)O)c2C(=O)O)(Oc2cccc(C(=O)O)c2C(=O)O)C=C1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.40
ELANE P08246 1/20 0.35
HSD17B10 Q99714 3/20 0.34
KDM4E B2RXH2 3/20 0.34
CDC25B P30305 2/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ESR1 P03372 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
HMGB1 P09429 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
GGT1 P19440 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
BLM P54132 1/20 0.34
NAPRT Q6XQN6 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649901 0.91 POLB (0.41) AKR1C3ELANEHSD17B10KDM4ECDC25B
SCHEMBL31018766 0.80 CA12 (0.34) HSD17B10KDM4ECDC25BALDH1A1ESR1
SCHEMBL2154321 0.79 ALDH1A1 (0.37) AKR1C3ELANEATMALDH1A1TDP1
SCHEMBL5267433 0.78 POLB (0.50) AKR1C3ELANEHSD17B10KDM4ECDC25B
SCHEMBL1444724 0.76 NPC1 (0.37) KDM4EALDH1A1HPGDABCB1LMNA
SCHEMBL210845 0.74 ALDH1A1 (0.38) ELANEHSD17B10KDM4EATMALDH1A1
SCHEMBL9680944 0.74 MEN1 (0.40) ELANEALDH1A1HPGDMAPK1LMNA
SCHEMBL10969617 0.74 CA12 (0.36) AKR1C3HSD17B10KDM4EALDH1A1ESR1
SCHEMBL4675282 0.73 GALK1 (0.36) HSD17B10CDC25BALDH1A1TDP1POLB
SCHEMBL1627987 0.73 PBRM1 (0.35) ELANEALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673872-B2 BLEND OF POLYIMIDE THERMOPLASTIC AND LOW VISCOSITY POLY(ARYLENE) ETHER GENERAL ELECTRIC COMPANY 2004-01-06 US claimed
US-20030125478-A1 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-07-03 US claimed
EP-0900828-A1 Polyetherimide resin/polyester resin blends GENERAL ELECTRIC COMPANY (US) 1999-03-10 EP disclosed
EP-0315025-A1 Amide-imide copolymers and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-10 EP disclosed