SCHEMBL5267433

SCHEMBL5267433

O=C(C1=CCC(Oc2ccc(C(=O)O)c(C(=O)O)c2)(Oc2ccc(C(=O)O)c(C(=O)O)c2)C=C1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.50
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
AKR1C3 P42330 1/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PYGM P11217 4/20 0.37
PYGL P06737 2/20 0.37
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
PGR P06401 1/20 0.36
CYP2D6 P10635 1/20 0.36
HPGD P15428 1/20 0.36
SLC6A2 P23975 1/20 0.36
PDE4A P27815 1/20 0.36
CYP2C19 P33261 1/20 0.36
HRH1 P35367 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649901 0.90 POLB (0.41) POLBALDH1A1KDM4EAKR1C3CDC25A
SCHEMBL2154321 0.85 ALDH1A1 (0.37) POLBALDH1A1AKR1C3TDP1L3MBTL1
SCHEMBL10893916 0.84 TDP1 (0.40) ALDH1A1MAPK1LMNACYP1A2PGR
SCHEMBL9680944 0.83 MEN1 (0.40) ALDH1A1MAPK1LMNACYP1A2PGR
SCHEMBL1627987 0.81 PBRM1 (0.35) POLBALDH1A1HPGDHTTMAPT
SCHEMBL29390518 0.81 PBRM1 (0.44) POLBALDH1A1AKR1C3MAPK1LMNA
SCHEMBL29865804 0.81 PBRM1 (0.44) POLBALDH1A1AKR1C3MAPK1LMNA
SCHEMBL9750704 0.81 PBRM1 (0.44) POLBALDH1A1AKR1C3MAPK1LMNA
SCHEMBL9716877 0.81 POLB (0.40) POLBALDH1A1KDM4ECDC25ACDC25B
SCHEMBL6537070 0.78 AKR1C3 (0.40) POLBALDH1A1KDM4EAKR1C3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828283-A2 POLYCARBONATE-ULTEM BLOCK COPOLYMERS General Electric Company (US) 2007-09-05 EP disclosed
WO-2006066055-A2 POLYCARBONATE-ULTEM BLOCK COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed
EP-1303571-B1 POLYIMIDE HYBRID ADHESIVES 3M INNOVATIVE PROPERTIES CO (US) 2004-05-26 EP disclosed
EP-1303571-A1 POLYIMIDE HYBRID ADHESIVES 3M Innovative Properties Company (US) 2003-04-23 EP disclosed
WO-2002004572-A1 POLYIMIDE HYBRID ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed
US-6294259-B1 EPOXY COMPONENT, AN EPOXY CURING AGENT, AND AN ENDCAPPED POLYIMIDE OLIGOMER FROM 4,4'-BIS(3,4-DICARBOXYPHENOXY)BISPHENOL A AND M-PHENYLENEDIAMINE 3M INNOVATIVE PROPERTIES COMPANY 2001-09-25 US disclosed
EP-0186243-B1 IMPACT MODIFIED POLYETHERIMIDE-POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 1993-02-03 EP disclosed
US-5166246-A Resistance to water absorption and swelling by adding a phenolic compound to the blend GENERAL ELECTRIC COMPANY (US) 1992-11-24 US disclosed
EP-0315025-A1 Amide-imide copolymers and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-10 EP disclosed
EP-0303598-A1 POLYETHERIMIDE-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1989-02-22 EP disclosed
US-4772653-A Stain resistant cookware from blends comprising an interpolymer of an unsaturated dicarboxylic acid compound AMOCO CORPORATION (US) 1988-09-20 US disclosed
WO-1988006170-A1 POLYETHERIMIDE-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO disclosed
US-4673708-A WITH ACRYLIC RUBBER GENERAL ELECTRIC COMPANY (US) 1987-06-16 US disclosed
EP-0224696-A2 Flame retardant polyetherimide-polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1987-06-10 EP disclosed
US-4629759-A BROMINATED POLYSTYRENE AND-OR ACRYLIC RUBBER COMPOSITE GENERAL ELECTRIC COMPANY (US) 1986-12-16 US disclosed
EP-0186243-A2 Impact modified polyetherimide-polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1986-07-02 EP disclosed
US-4585852-A MELT POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 1986-04-29 US disclosed
EP-0120184-A2 Continuous process for preparing polyetherimides GENERAL ELECTRIC COMPANY (US) 1984-10-03 EP disclosed