SCHEMBL6537209

SCHEMBL6537209

Cc1ccc(NC(=O)CC(=O)c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.71
NPC1 O15118 8/20 0.71
KMT2A Q03164 8/20 0.71
MEN1 O00255 6/20 0.69
POLB P06746 3/20 0.67
SMN1; SMN2 Q16637 3/20 0.64
MAPT P10636 3/20 0.64
ALDH1A1 P00352 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
TP53 P04637 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696576 0.93 KMT2A (0.68) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL20851771 0.91 POLB (0.74) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL11782142 0.91 KMT2A (0.83) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL1098345 0.87 RAB9A (0.77) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL1957664 0.87 KMT2A (0.73) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL14890950 0.85 RAB9A (0.74) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL6650154 0.85 KMT2A (0.68) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL7823059 0.84 RAB9A (0.73) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL11572863 0.83 RAB9A (0.71) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL25986986 0.83 SMN1; SMN2 (0.65) RAB9ANPC1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4402700-A CONDITIONING CLAIROL INCORPORATED (US) 1983-09-06 US claimed
US-4119399-A AQUEOUS, ALKALINE CLAIROL INCORPORATED (US) 1978-10-10 US claimed
CN-108218869-B Synthesis method of pyrazolo [3,4-b ] pyrrolo [3,4-d ] pyridine derivative 苏州大学 2020-06-05 CN disclosed
US-6824953-B2 POLYMERIZABLE COMPOUND HAVING AN ETHYLENIC UNSATURATED BOND, A METHINE DYE, AND A RADICAL GENERATOR THAT INTERACTS WITH THE DYE TO GENERATE A RADICAL FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
US-20020182530-A1 Polymerizable compound having an ethylenic unsaturated bond, a methine dye, and a radical generator that interacts with the dye to generate a radical FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
US-5998082-A DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0803377-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 1999-11-24 EP disclosed
EP-0803377-A1 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
US-4838894-A SUBSTITUTED M-AMINOPHENOLS; OXIDATION DYES CLAIROL INCORPORATED (US) 1989-06-13 US disclosed
EP-0215560-A1 Hair dye coupler and process for making Bristol-Myers Company (US) 1987-03-25 EP disclosed
US-4566876-A COLORFAST SHADES OF BLUE AND BROWN CLAIROL INCORPORATED (US) 1986-01-28 US disclosed
US-4532127-A Two part composition comprising aqueous base containing alkalizing agent and quaternary amine, oxidizing solution CLAIROL INCORPORATED (US) 1985-07-30 US disclosed
US-4402700-A CONDITIONING CLAIROL INCORPORATED (US) 1983-09-06 US disclosed
US-4196145-A OXIDATION COLOR DYES CLAIROL INCORPORATED (US) 1980-04-01 US disclosed
US-4119399-A AQUEOUS, ALKALINE CLAIROL INCORPORATED (US) 1978-10-10 US disclosed
US-4096243-A Composition for lightening hair containing an oxidizing agent and certain quaternary amines CLAIROL INCORPORATED (US) 1978-06-20 US disclosed
US-4092102-A HAIR DYES, OXIDATION DYES CLAIROL INCORPORATED (US) 1978-05-30 US disclosed
US-3970423-A PHENYLENEDIAMINE DERIVATIVES CLAIROL INCORPORATED (US) 1976-07-20 US disclosed