Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25986986 | 0.92 | SMN1; SMN2 (0.65) | POLBKMT2AMEN1ATMNPC1 | |
| SCHEMBL7696576 | 0.91 | KMT2A (0.68) | POLBKMT2AMEN1ATMNPC1 | |
| SCHEMBL6537209 | 0.91 | RAB9A (0.71) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6627891 | 0.89 | KMT2A (0.69) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8141144 | 0.86 | POLB (1.00) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL600578 | 0.81 | RAB9A (0.83) | POLBKMT2AMEN1ATMNPC1 | |
| SCHEMBL12629995 | 0.81 | KMT2A (0.84) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3317511 | 0.81 | CA12 (0.62) | POLBKMT2AMEN1HDAC3HDAC4 | |
| SCHEMBL11572863 | 0.80 | RAB9A (0.71) | KMT2AMEN1NPC1RAB9AHDAC3 | |
| SCHEMBL1201297 | 0.80 | KMT2A (0.62) | POLBKMT2AMEN1ATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056515-A1 | MULTI-SUBSTITUTED QUINOLINE-COORDINATED IRIDIUM-HYBRIDIZED COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京工业大学 | 2019-03-28 | — | — | WO | disclosed |