SCHEMBL653727

SCHEMBL653727

Brc1ccc(C(Br)(c2ccccc2)C(Br)(Br)Br)c(Br)c1Br

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
KCNN4 O15554 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812616 0.89
SCHEMBL4951380 0.85
SCHEMBL653490 0.84 CA1 (0.32) TSHRKCNN4ALDH1A1
SCHEMBL653858 0.82 TDP1 (0.30)
SCHEMBL27646568 0.79 TSHR (0.32) TSHRKCNN4ALDH1A1
SCHEMBL652272 0.77 CA1 (0.38) TSHRKCNN4ALDH1A1
SCHEMBL29196988 0.76 CYP2C9 (0.41) TSHRKCNN4ALDH1A1
SCHEMBL4805416 0.75
SCHEMBL4951332 0.74 ALDH1A1 (0.32) KCNN4ALDH1A1
SCHEMBL15864558 0.73 ESR1 (0.34) KCNN4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776859-B Preparation, separation and purification method of decabromodiphenyl ethane debromination product 山东科技大学 2024-05-17 CN claimed
CN-117776859-A Preparation, separation and purification method of decabromodiphenyl ethane debromination product 山东科技大学 2024-03-29 CN claimed
US-8354464-B2 Mixtures of brominated diphenylethanes, method of preparing the same and resin composition using the same CHEIL INDUSTRIES INC. (KR) 2013-01-15 US claimed
US-8334332-B2 Flame-retardant thermoplastic resin composition with excellent color tone CHEIL INDUSTRIES INC. (KR) 2012-12-18 US claimed
US-8329804-B2 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2012-12-11 US claimed
US-8193272-B2 Flame-retardant high impact vinyl aromatic resin composition having good fluidity CHEIL INDUSTRIES INC. (KR) 2012-06-05 US claimed
US-8119720-B2 Thermoplastic resin composition having improved flowability CHEIL INDUSTRIES INC. (KR) 2012-02-21 US claimed
US-7977421-B2 Brominated diphenyl ethane mixtures and resin compositions including the same CHEIL INDUSTRIES INC. (KR) 2011-07-12 US claimed
US-20110160343-A1 Flame-Retardant Thermoplastic Resin Composition with Excellent Color Tone CHEIL INDUSTRIES INC. (KR) 2011-06-30 US claimed
US-20100168292-A1 Thermoplastic Resin Composition Having Improved Flowability CHEIL INDUSTRIES INC. (KR) 2010-07-01 US claimed
US-20100152372-A1 Flame Retardant Thermoplastic Resin Composition CHEIL INDUSTRIES INC. (KR) 2010-06-17 US claimed
US-20100029828-A1 Brominated Diphenyl Ethane Mixtures and Resin Compositions Including the Same CHEIL INDUSTRIES INC. (KR) 2010-02-04 US claimed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-6117371-A FLAME RETARDANT OF HEXABROMODIPHENYLALKANE, HEPTABROMODIPHENYLALKANE, AND OCTABROMODIPHENYLALKANE WHICH HAS A BROAD MELTING POINT RANGE; FLAMMABLE POLYMER AND FLAME RETARDANT GREAT LAKES CHEMICAL CORPORATION (US) 2000-09-12 US claimed
EP-0502333-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-09-09 EP claimed
EP-0490378-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-06-17 EP claimed
US-5055235-A Heating non-condensed ring polyaromatics in the presence of bromine and a halogenation catalyst ETHYL CORPORATION (US) 1991-10-08 US claimed
EP-0445595-A2 Bromination process ALBEMARLE CORPORATION (US) 1991-09-11 EP claimed
US-5039729-A Consisting of hexabromodiphenyl ethane, heptabromodiphenyl ethane and octabromodiphenyl ethane; flame retarders ETHYL CORPORATION (US) 1991-08-13 US claimed