Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 9/20 | 0.35 |
| ▸ | BCHE | P06276 | 6/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725924 | 0.72 | MRGPRX2 (0.40) | AR | |
| SCHEMBL11326119 | 0.71 | AR (0.39) | MAPTALDH1A1HPGDSMN1; SMN2AR | |
| SCHEMBL11516736 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HPGDHTTLMNASMN1; SMN2 | |
| SCHEMBL11515721 | 0.69 | CREBBP (0.53) | MEN1KMT2AACHE | |
| SCHEMBL9176307 | 0.67 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4135469 | 0.66 | TDP1 (0.47) | MAPTALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL29835939 | 0.65 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6874618 | 0.65 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27527087 | 0.64 | GLA (0.41) | MAPTALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL7910581 | 0.63 | GLA (0.53) | GLAGAASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828116-B1 | Energy transfer assay method and reagent | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2004-12-07 | — | — | US | disclosed |
| EP-1086179-B1 | ENERGY TRANSFER ASSAY METHOD AND REAGENT | AMERSHAM BIOSCIENCES UK LTD (GB) | 2003-04-23 | — | — | EP | disclosed |
| EP-1086179-A1 | ENERGY TRANSFER ASSAY METHOD AND REAGENT | Amersham Pharmacia Biotech UK Ltd. (GB) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064519-A1 | ENERGY TRANSFER ASSAY METHOD AND REAGENT | AMERSHAM BIOSCIENCES CORP (GB) | 1999-12-16 | — | — | WO | disclosed |