Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537507 | 0.93 | SLC16A3 (0.36) | SLC16A3TMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL6537542 | 0.91 | PTGES (0.36) | SLC16A3MEN1KMT2ATYK2POLB | |
| SCHEMBL6537960 | 0.87 | SLC16A3 (0.38) | SLC16A3MEN1KMT2ATYK2POLB | |
| SCHEMBL8471309 | 0.87 | KMT2A (0.34) | SLC16A3MEN1KMT2ATYK2POLB | |
| SCHEMBL6537654 | 0.83 | KMT2A (0.35) | SLC16A3MEN1KMT2ATYK2POLB | |
| SCHEMBL8588646 | 0.78 | SLC16A3 (0.39) | SLC16A3MEN1KMT2ATYK2POLB | |
| SCHEMBL6537404 | 0.77 | SLC16A3 (0.36) | SLC16A3TMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL6537957 | 0.75 | TYK2 (0.44) | SLC16A3TMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL6537510 | 0.71 | SLC16A3 (0.37) | SLC16A3MEN1KMT2ATYK2POLB | |
| SCHEMBL6537689 | 0.71 | SLC16A3 (0.40) | SLC16A3TMEM97SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |