Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537960 | 0.85 | SLC16A3 (0.38) | SLC16A3HAVCR2MAPTPLECPTPN1 | |
| SCHEMBL6537507 | 0.79 | SLC16A3 (0.36) | SLC16A3ITGB1ITGA4MAPTCDK2 | |
| SCHEMBL6537961 | 0.79 | SLC16A3 (0.41) | SLC16A3HAVCR2MAPTPLECPTPN1 | |
| SCHEMBL6537735 | 0.78 | SLC16A3 (0.47) | SLC16A3HAVCR2MAPTPLECCDK2 | |
| SCHEMBL6537405 | 0.78 | SLC16A3 (0.35) | SLC16A3MAPTCDK2MEN1KMT2A | |
| SCHEMBL8471309 | 0.77 | KMT2A (0.34) | SLC16A3ITGB1ITGA4MAPTMEN1 | |
| SCHEMBL6537542 | 0.77 | PTGES (0.36) | SLC16A3MEN1KMT2AJAK2JAK1 | |
| SCHEMBL6537654 | 0.77 | KMT2A (0.35) | SLC16A3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8588641 | 0.76 | SLC16A3 (0.41) | SLC16A3HAVCR2MAPTPLECPTPN1 | |
| SCHEMBL8476104 | 0.73 | HAVCR2 (0.50) | SLC16A3HAVCR2MAPTPLECMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |