Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CDK14 | O94921 | 3/20 | 0.41 |
| ▸ | CCNY | Q8ND76 | 3/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537554 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6538057 | 0.87 | RAB9A (0.49) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6538053 | 0.87 | RAB9A (0.49) | SMN1; SMN2MAPTHTTLMNATSHR | |
| Hydrochloric Acid SCHEMBL6538237 | 0.85 | KDR (0.43) | SMN1; SMN2MAPTHTTLMNATSHR | |
| Hydrochloric Acid SCHEMBL6538232 | 0.85 | KDR (0.43) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6537149 | 0.84 | MAPT (0.45) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6537152 | 0.84 | MAPT (0.45) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6537852 | 0.82 | KDR (0.48) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6537730 | 0.82 | PARP1 (0.52) | SMN1; SMN2MAPTHTTLMNATSHR | |
| SCHEMBL6537382 | 0.78 | SLC40A1 (0.52) | SMN1; SMN2MAPTHTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |