Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 15/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539510 | 0.93 | ADRB1 (0.59) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6539299 | 0.88 | ADRB3 (0.57) | ADRB1ADRB3NPC1MEN1RAB9A | |
| SCHEMBL6538564 | 0.84 | ADRB3 (0.55) | ADRB1ADRB3NPC1MEN1RAB9A | |
| SCHEMBL6539710 | 0.83 | ADRB1 (0.53) | ADRB1ADRB3NPC1MEN1RAB9A | |
| SCHEMBL6540414 | 0.82 | ADRB1 (0.53) | ADRB1ADRB3NPC1MEN1RAB9A | |
| SCHEMBL6539156 | 0.82 | ADRB1 (0.53) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6538911 | 0.81 | ADRB3 (0.56) | ADRB1ADRB3NPC1MEN1RAB9A | |
| SCHEMBL6539352 | 0.81 | ADRB1 (0.62) | ADRB1ADRB3NPC1MEN1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6539771 | 0.81 | ADRB3 (0.73) | ADRB1ADRB3NPC1MEN1RAB9A | |
| SCHEMBL6539792 | 0.79 | ADRB1 (0.53) | ADRB1ADRB3NPC1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |