SCHEMBL6538841

SCHEMBL6538841

COc1ccc(N(c2ccc(OC)cc2)c2ccccc2N)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.45
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
HTT P42858 1/20 0.45
RECQL P46063 1/20 0.45
MMP14 P50281 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.42
CA4 P22748 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520359 0.80 ALDH1A1 (0.48) TDP1ALDH1A1KDM4EMEN1GAA
SCHEMBL2009250 0.80 ALDH1A1 (0.48) TDP1ALDH1A1KDM4EMEN1GAA
SCHEMBL8943802 0.79 PTGES (0.51) ALDH1A1GAAMAPTHTTRAB9A
SCHEMBL30353938 0.78 CA4 (0.41) TDP1ALDH1A1KDM4EMAPTRAB9A
SCHEMBL388104 0.78 ALDH1A1 (0.52) TDP1ALDH1A1KDM4EMEN1GAA
SCHEMBL30221915 0.78 ALDH1A1 (0.52) TDP1ALDH1A1KDM4EMEN1GAA
SCHEMBL12201054 0.77 CNR2 (0.49) TDP1ALDH1A1MEN1MAPTKMT2A
SCHEMBL10053559 0.76 CA4 (0.45) ALDH1A1KDM4EMEN1KMT2AMAPK1
SCHEMBL13720711 0.76 CA4 (0.59) TDP1ALDH1A1KDM4EMAPTKMT2A
SCHEMBL13720596 0.76 CA4 (0.59) TDP1ALDH1A1KDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1407500-A1 ELECTROACTIVE POLYMERS AND DEVICES MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-04-14 EP claimed
WO-2003007395-A1 ELECTROACTIVE POLYMERS AND DEVICES MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-01-23 WO claimed