SCHEMBL6538871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3099432	0.84	NOTUM (0.49)	NPC1MAPTMEN1KMT2ARAB9A
	SCHEMBL791985	0.75	MAOB (0.69)	MAOBMAOANPC1L3MBTL1MAPT
	SCHEMBL6540192	0.73	MEN1 (0.47)	MAOBL3MBTL1MAPTMAPK1NPSR1
	SCHEMBL20367158	0.72	GSTP1 (0.63)	MAOBGSTP1NPC1APPMEN1
	SCHEMBL19091938	0.72	GSTP1 (0.63)	MAOBGSTP1NPC1APPMEN1
	Benzylphenylether SCHEMBL28164613	0.72	MAOB (0.75)	MAOBMAOANPC1L3MBTL1MAPT
	SCHEMBL6207736	0.72	NPSR1 (0.54)	MAOBNPC1ATML3MBTL1MAPT
	SCHEMBL10517455	0.71	GSTP1 (0.51)	MAOBGSTP1NPC1MAPTMAPK1
	SCHEMBL6265431	0.71	NPSR1 (0.53)	MAOBGSTP1NPC1L3MBTL1MAPT
	SCHEMBL6539139	0.71	NPSR1 (0.53)	MAOBGSTP1NPC1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.