Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540567 | 0.92 | ALDH1A1 (0.39) | ALDH1A1DYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL6539135 | 0.87 | PPARD (0.39) | HDAC6PPARDMEN1KMT2AHDAC4 | |
| SCHEMBL6207411 | 0.85 | PPARD (0.41) | ALDH1A1HDAC6DYRK3ROCK2PRKD3 | |
| SCHEMBL6234392 | 0.84 | PPARD (0.41) | ALDH1A1HDAC6CDK2GSK3BMKNK2 | |
| SCHEMBL6538917 | 0.84 | PPARD (0.42) | HDAC6MKNK2PPARDMEN1KMT2A | |
| SCHEMBL6234081 | 0.83 | PPARD (0.39) | HDAC6MKNK2PPARDMEN1KMT2A | |
| SCHEMBL6540528 | 0.83 | ALDH1A1 (0.38) | ALDH1A1DYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL6540113 | 0.83 | TP53 (0.39) | ALDH1A1DYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL6539836 | 0.82 | RCE1 (0.43) | HDAC6MKNK2PPARDMEN1KMT2A | |
| SCHEMBL6540424 | 0.81 | ALDH1A1 (0.42) | ALDH1A1DYRK3ROCK2PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | ALDH1A1 163/4885HDAC6 1851/4885DYRK3 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.