Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 5/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | HCK | P08631 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 3/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538377 | 0.90 | SRC (0.41) | ABL1SRCPIK3CDEGFRHCK | |
| SCHEMBL6538926 | 0.89 | POLB (0.39) | ADORA2AADORA1RETABL1SRC | |
| SCHEMBL6538508 | 0.87 | SRC (0.43) | ABL1SRCMEN1KMT2APIK3CD | |
| SCHEMBL6538300 | 0.83 | PIK3CG (0.46) | ADORA2AADORA1ABL1SRCPIK3CD | |
| SCHEMBL5148931 | 0.82 | ADORA2A (0.46) | ADORA2AADORA1RETHDAC6ABL1 | |
| SCHEMBL6538398 | 0.82 | ADORA2A (0.50) | ADORA2AADORA1RETHDAC6MAPK14 | |
| SCHEMBL6539151 | 0.81 | ABL1 (0.48) | ADORA2AADORA1ABL1SRCPIK3CD | |
| SCHEMBL6539117 | 0.80 | PDE1A (0.43) | ADORA2AADORA1ABL1SRCMEN1 | |
| SCHEMBL6134450 | 0.80 | ADORA1 (0.50) | ADORA2AADORA1RETMAPK14KMT2A | |
| SCHEMBL6538407 | 0.80 | CA2 (0.38) | ABL1SRCMEN1KMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | ADORA1, ADORA2A, P2RX5 | ADORA2A 2/4885ADORA1 1/4885RET 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.