Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 4/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232912 | 0.81 | MEN1 (0.48) | PPARDOXTR | |
| SCHEMBL6538971 | 0.81 | PPARD (0.40) | PPARDTAAR1OXTRRCE1HDAC6 | |
| SCHEMBL6232652 | 0.77 | TAAR1 (0.41) | PPARDTAAR1OXTRRCE1HDAC6 | |
| SCHEMBL6235990 | 0.76 | PPARD (0.43) | PPARDTAAR1RCE1HDAC6MKNK1 | |
| SCHEMBL6538951 | 0.75 | PPARD (0.38) | PPARD | |
| Hydrochloric Acid SCHEMBL6540242 | 0.75 | OXTR (0.40) | PPARDTAAR1OXTRRCE1HDAC6 | |
| SCHEMBL6539048 | 0.75 | PPARD (0.40) | PPARDTAAR1OXTRRCE1HDAC6 | |
| SCHEMBL6539397 | 0.75 | NR4A2 (0.44) | PPARDGPBAR1 | |
| SCHEMBL6208169 | 0.73 | PPARD (0.42) | PPARDTAAR1OXTRRCE1HDAC6 | |
| SCHEMBL6256472 | 0.73 | PPARD (0.41) | PPARDTAAR1OXTRRCE1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | PPARD 1747/4885TAAR1 1264/4885OXTR 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.