Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973190 | 0.93 | BACE1 (0.48) | BACE1AKT1HDAC3HDAC1HDAC2 | |
| SCHEMBL27459831 | 0.93 | BACE1 (0.48) | BACE1AKT1HDAC3HDAC1HDAC2 | |
| SCHEMBL27511976 | 0.87 | BACE1 (0.45) | BACE1AKT1HDAC3HDAC1HDAC2 | |
| SCHEMBL1971865 | 0.86 | ALDH1A1 (0.42) | AKT1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL28175486 | 0.86 | ALDH1A1 (0.42) | AKT1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4584497 | 0.85 | BACE1 (0.56) | BACE1ALDH1A1MEN1KMT2AITGA4 | |
| SCHEMBL4584501 | 0.85 | BACE1 (0.56) | BACE1ALDH1A1MEN1KMT2AITGA4 | |
| SCHEMBL6540352 | 0.85 | MEN1 (0.42) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL6539625 | 0.83 | BACE1 (0.44) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9115215 | 0.82 | ATM (0.47) | BACE1AKT1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | BACE1 3900/4885AKT1 3167/4885HDAC3 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.