Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012916 | 0.91 | MEN1 (0.49) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL6539436 | 0.85 | BACE1 (0.45) | MEN1KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL6540317 | 0.79 | TAS2R14 (0.50) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL2268145 | 0.76 | MEN1 (0.47) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL1024207 | 0.76 | KMT2A (0.47) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL18341181 | 0.76 | KMT2A (0.47) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| SCHEMBL1642165 | 0.76 | KMT2A (0.51) | MEN1KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL18341183 | 0.76 | KMT2A (0.47) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20974171 | 0.75 | KMT2A (0.46) | MEN1KMT2AHPGDCYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20974172 | 0.75 | KMT2A (0.46) | MEN1KMT2AHPGDCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | MEN1 4140/4885KMT2A 432/4885FPR2 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.