Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 14/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6538979 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1 | |
| SCHEMBL6538446 | 0.85 | ADRB3 (0.80) | ADRB3ADRB1 | |
| SCHEMBL6539609 | 0.84 | ADRB3 (0.72) | ADRB3ADRB1NR1H4DEGS1 | |
| SCHEMBL6538626 | 0.83 | ADRB3 (1.00) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL7558333 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1 | |
| SCHEMBL6538711 | 0.82 | ADRB3 (0.82) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL6538594 | 0.82 | ADRB3 (0.98) | ADRB3ADRB1 | |
| SCHEMBL6538997 | 0.82 | ADRB3 (0.82) | ADRB3ADRB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6538601 | 0.82 | ADRB1 (0.66) | ADRB3ADRB1KMT2A | |
| SCHEMBL6538702 | 0.82 | ADRB3 (0.74) | ADRB3ADRB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | claimed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | claimed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | claimed |
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |