Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232652 | 0.88 | TAAR1 (0.41) | HRH3ALDH1A1PPARDTAAR1RCE1 | |
| SCHEMBL6539472 | 0.87 | HRH3 (0.38) | HRH3PPARDTAAR1RCE1CDK2 | |
| Hydrochloric Acid SCHEMBL6540242 | 0.85 | OXTR (0.40) | HRH3ALDH1A1PPARDTAAR1RCE1 | |
| SCHEMBL6539374 | 0.85 | PPARD (0.37) | ALDH1A1PPARDTAAR1RCE1DYRK3 | |
| SCHEMBL6539690 | 0.83 | HPGD (0.42) | HRH3ALDH1A1PPARDTAAR1RCE1 | |
| SCHEMBL6539662 | 0.82 | PPARD (0.41) | PPARDTAAR1RCE1MKNK2OXTR | |
| SCHEMBL6539798 | 0.81 | GSK3B (0.36) | ALDH1A1PPARDTAAR1RCE1DYRK3 | |
| SCHEMBL6539804 | 0.81 | GSK3B (0.36) | ALDH1A1PPARDTAAR1RCE1DYRK3 | |
| SCHEMBL6539033 | 0.81 | MEN1 (0.48) | ALDH1A1PPARDOXTRMEN1KMT2A | |
| SCHEMBL6539048 | 0.81 | PPARD (0.40) | HRH3ALDH1A1PPARDTAAR1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | HRH3 940/4885ALDH1A1 163/4885PPARD 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.