Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042715 | 0.87 | OPRD1 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL6538563 | 0.86 | ADRB1 (0.54) | RAB9ANPC1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL6538732 | 0.83 | ADRB1 (0.50) | RAB9ANPC1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL6539381 | 0.81 | ADRB1 (0.54) | RAB9ANPC1ADRB1ADRB3ADRB2 | |
| SCHEMBL6540060 | 0.81 | ADRB1 (0.48) | RAB9ANPC1ADRB1ADRB3ADRB2 | |
| SCHEMBL6538663 | 0.81 | ADRB1 (0.48) | RAB9ANPC1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL6539431 | 0.80 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL6539512 | 0.80 | ADRB1 (0.52) | RAB9ANPC1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL6539030 | 0.80 | KDM4E (0.47) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL6538597 | 0.80 | NR1H4 (0.48) | RAB9ANPC1ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |