Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 8/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539387 | 0.88 | PPARD (0.47) | NPSR1ALDH1A1LMNAHTTPPARD | |
| SCHEMBL6207736 | 0.83 | NPSR1 (0.54) | NPSR1ALDH1A1LMNAHTTPPARD | |
| SCHEMBL6236506 | 0.82 | PPARD (0.43) | NPSR1ALDH1A1PPARDMAPTMEN1 | |
| SCHEMBL6208499 | 0.82 | NPSR1 (0.56) | NPSR1ALDH1A1LMNAHTTPPARD | |
| SCHEMBL6538977 | 0.82 | LMNA (0.50) | NPSR1ALDH1A1LMNAHTTPPARD | |
| SCHEMBL6233752 | 0.82 | LMNA (0.50) | NPSR1ALDH1A1LMNAHTTPPARD | |
| SCHEMBL6538831 | 0.82 | ESR2 (0.47) | NPSR1ALDH1A1PPARDMAPTMEN1 | |
| SCHEMBL6232537 | 0.81 | KMT2A (0.41) | NPSR1ALDH1A1PPARDMAPTMEN1 | |
| SCHEMBL6231803 | 0.81 | PPARD (0.54) | NPSR1ALDH1A1LMNAHTTPPARD | |
| SCHEMBL6539039 | 0.81 | NPSR1 (0.54) | NPSR1ALDH1A1LMNAHTTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | NPSR1 884/4885ALDH1A1 163/4885LMNA 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.