SCHEMBL6539740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6539836	0.89	RCE1 (0.43)	PPARDCYP2A6MKNK1MKNK2RCE1
	SCHEMBL6233212	0.89	HSD17B1 (0.42)	HSD17B1HSD17B2PPARDFYNCYP2A6
	SCHEMBL6538917	0.85	PPARD (0.42)	HSD17B1HSD17B2PPARDCYP2A6MKNK1
	SCHEMBL6540055	0.82	PPARD (0.53)	PPARDRCE1
	SCHEMBL6539132	0.82	MEN1 (0.45)	PPARDMEN1KMT2AATR
	SCHEMBL6230071	0.82	ESR2 (0.47)	PPARDMEN1KMT2A
	SCHEMBL6539500	0.82	ESR2 (0.47)	PPARDMEN1KMT2A
	SCHEMBL6234081	0.82	PPARD (0.39)	PPARDMKNK1MKNK2RCE1MEN1
	SCHEMBL6539547	0.81	PPARD (0.44)	HSD17B1HSD17B2PPARDFYNCYP2A6
	SCHEMBL6539478	0.79	HSD17B1 (0.42)	HSD17B1HSD17B2PPARDFYNCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.