Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540195 | 1.00 | CCR3 (0.37) | CCR3NAMPTALDH1A1EGFRERBB2 | |
| SCHEMBL6541124 | 0.91 | NAMPT (0.42) | NAMPTALDH1A1 | |
| SCHEMBL6541119 | 0.91 | NAMPT (0.42) | NAMPTALDH1A1 | |
| SCHEMBL6540931 | 0.86 | PKM (0.44) | NAMPTALDH1A1EGFRERBB2MEN1 | |
| SCHEMBL6540934 | 0.86 | PKM (0.44) | NAMPTALDH1A1EGFRERBB2MEN1 | |
| SCHEMBL6540891 | 0.86 | CCR3 (0.35) | CCR3MEN1KMT2ATP53CACNA1G | |
| SCHEMBL6540884 | 0.86 | CCR3 (0.35) | CCR3MEN1KMT2ATP53CACNA1G | |
| SCHEMBL6541605 | 0.81 | KMT2A (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6541597 | 0.81 | KMT2A (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6541438 | 0.81 | CAPN1 (0.38) | ALDH1A1MAPTKMT2ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | CCR3 1167/4885NAMPT 4409/4885ALDH1A1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.