Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 13/20 | 0.40 |
| ▸ | CA2 | P00918 | 13/20 | 0.40 |
| ▸ | CA4 | P22748 | 13/20 | 0.40 |
| ▸ | CA9 | Q16790 | 13/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541119 | 1.00 | NAMPT (0.42) | NAMPTCA1CA2CA4CA9 | |
| SCHEMBL6540195 | 0.91 | CCR3 (0.37) | NAMPTALDH1A1 | |
| SCHEMBL6540189 | 0.91 | CCR3 (0.37) | NAMPTALDH1A1 | |
| SCHEMBL6540934 | 0.89 | PKM (0.44) | NAMPTALDH1A1 | |
| SCHEMBL6540931 | 0.89 | PKM (0.44) | NAMPTALDH1A1 | |
| SCHEMBL6541597 | 0.88 | KMT2A (0.38) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL6541605 | 0.88 | KMT2A (0.38) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL6541438 | 0.83 | CAPN1 (0.38) | CA2ABCB1ALDH1A1HSD17B10 | |
| SCHEMBL6541442 | 0.83 | CAPN1 (0.38) | CA2ABCB1ALDH1A1HSD17B10 | |
| SCHEMBL6541230 | 0.83 | ALDH1A1 (0.39) | ABCB1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | NAMPT 4409/4885CA1 4181/4885CA2 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.