Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA4 | P22748 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540209 | 1.00 | ADRB1 (0.42) | ADRB1PTPN1ADRB3ADRB2ADRA1D | |
| SCHEMBL6552712 | 0.90 | KCNH2 (0.37) | ADRB1ADRB3ADRB2CYP1A2CYP2D6 | |
| SCHEMBL6540723 | 0.89 | ADRB3 (0.53) | ADRB1ADRB3ADRB2ADRA1DADRA1A | |
| SCHEMBL6540725 | 0.89 | ADRB3 (0.53) | ADRB1ADRB3ADRB2ADRA1DADRA1A | |
| SCHEMBL6540720 | 0.89 | ADRB3 (0.53) | ADRB1ADRB3ADRB2ADRA1DADRA1A | |
| SCHEMBL6552709 | 0.88 | KCNH2 (0.36) | ADRB1ADRB3ADRB2CYP1A2CYP2D6 | |
| SCHEMBL6272447 | 0.88 | ADRB3 (0.39) | ADRB1ADRB3KCNH2 | |
| SCHEMBL6272453 | 0.88 | ADRB3 (0.39) | ADRB1ADRB3KCNH2 | |
| SCHEMBL6540314 | 0.88 | ADRB3 (0.41) | ADRB1ADRB3ADRB2KCNH2 | |
| SCHEMBL6540307 | 0.88 | ADRB3 (0.41) | ADRB1ADRB3ADRB2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB1 7/4885PTPN1 4443/4885ADRB3 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.