Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552712 | 0.92 | KCNH2 (0.37) | KCNH2ADRB3ADRB1MEN1POLB | |
| SCHEMBL6552641 | 0.91 | KCNH2 (0.42) | KCNH2ADRB3ADRB1ADRB2TAS2R14 | |
| SCHEMBL6540202 | 0.88 | ADRB1 (0.42) | KCNH2ADRB3ADRB1ADRB2CYP1A2 | |
| SCHEMBL6540209 | 0.88 | ADRB1 (0.42) | KCNH2ADRB3ADRB1ADRB2CYP1A2 | |
| SCHEMBL6540307 | 0.87 | ADRB3 (0.41) | KCNH2ADRB3ADRB1MEN1POLB | |
| SCHEMBL6540314 | 0.87 | ADRB3 (0.41) | KCNH2ADRB3ADRB1MEN1POLB | |
| SCHEMBL6272447 | 0.85 | ADRB3 (0.39) | KCNH2ADRB3ADRB1MEN1POLB | |
| SCHEMBL6272453 | 0.85 | ADRB3 (0.39) | KCNH2ADRB3ADRB1MEN1POLB | |
| SCHEMBL6553145 | 0.85 | KCNH2 (0.42) | KCNH2ADRB3ADRB1POLBADRB2 | |
| SCHEMBL6552642 | 0.85 | KCNH2 (0.42) | KCNH2ADRB3ADRB1POLBADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |