Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539222 | 0.92 | ADRB3 (0.51) | ADRB2ADRB1HTR1AADRB3KCNH2 | |
| SCHEMBL6539213 | 0.92 | ADRB3 (0.51) | ADRB2ADRB1HTR1AADRB3KCNH2 | |
| SCHEMBL6540485 | 0.85 | ALDH1A1 (0.55) | POLBL3MBTL1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL6540945 | 0.85 | ALDH1A1 (0.55) | POLBL3MBTL1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL6540926 | 0.83 | ALDH1A1 (0.53) | POLBL3MBTL1KCNH2ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6541835 | 0.80 | ADRB3 (0.64) | ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6541845 | 0.80 | ADRB3 (0.64) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6540084 | 0.79 | ADRB3 (0.53) | ADRB2ADRB1HTR1AADRB3KCNH2 | |
| SCHEMBL6540079 | 0.79 | ADRB3 (0.53) | ADRB2ADRB1HTR1AADRB3KCNH2 | |
| SCHEMBL6540800 | 0.77 | ALDH1A1 (0.61) | POLBKCNH2ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB2 4/4885ADRB1 7/4885HTR1A 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.