Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540079 | 1.00 | ADRB3 (0.53) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6539213 | 0.87 | ADRB3 (0.51) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6539222 | 0.87 | ADRB3 (0.51) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6540397 | 0.82 | ALDH1A1 (0.58) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6540390 | 0.82 | ALDH1A1 (0.58) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6540571 | 0.81 | ADRB3 (0.61) | ADRB3ADRB1ADRB2MAPTTLR4 | |
| SCHEMBL6552584 | 0.80 | ADRB3 (0.43) | ADRB3ADRB1ADRB2MAPTCYP2C19 | |
| SCHEMBL5375723 | 0.80 | ADRB2 (0.62) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL13206947 | 0.79 | ADRB2 (0.49) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6540236 | 0.79 | ADRB2 (0.47) | ADRB3ADRB1ADRB2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB3 58/4885ADRB1 7/4885ADRB2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.