Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540282 | 1.00 | ADRB3 (0.42) | ADRB3ADRB1AKR1C3BACE1 | |
| SCHEMBL6541176 | 0.94 | ADRB3 (0.46) | ADRB3ADRB1BACE1 | |
| SCHEMBL6541170 | 0.94 | ADRB3 (0.46) | ADRB3ADRB1BACE1 | |
| SCHEMBL6804154 | 0.93 | ADRB3 (0.52) | ADRB3ADRB1 | |
| SCHEMBL6540553 | 0.93 | CCR5 (0.38) | ADRB3ADRB1BACE1 | |
| SCHEMBL6540558 | 0.93 | CCR5 (0.38) | ADRB3ADRB1BACE1 | |
| SCHEMBL6677354 | 0.92 | ADRB3 (0.50) | ADRB3ADRB1 | |
| SCHEMBL6677324 | 0.91 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6540663 | 0.91 | CYP4F2 (0.36) | ADRB3BACE1 | |
| SCHEMBL6539911 | 0.91 | ADRB3 (0.36) | ADRB3ADRB1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ADRB3 58/4885ADRB1 7/4885AKR1C3 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.