Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539899 | 0.93 | RCE1 (0.42) | HDAC3HDAC1HDAC2NCOR2LPAR1 | |
| SCHEMBL6540212 | 0.85 | LPAR1 (0.39) | HDAC3HDAC1HDAC2NCOR2LPAR1 | |
| SCHEMBL6540802 | 0.81 | HDAC3 (0.42) | HDAC3HDAC1HDAC2NCOR2LPAR1 | |
| SCHEMBL6541405 | 0.78 | LPAR1 (0.54) | HDAC3HDAC1HDAC2NCOR2TDP1 | |
| SCHEMBL22449040 | 0.78 | HDAC3 (0.41) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL6540935 | 0.77 | LPAR1 (0.48) | HDAC3HDAC1HDAC2NCOR2LPAR1 | |
| SCHEMBL6541235 | 0.77 | HDAC3 (0.56) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL6539552 | 0.76 | HTR6 (0.39) | HDAC3HDAC1HDAC2NCOR2LPAR1 | |
| SCHEMBL6539902 | 0.76 | HDAC1 (0.49) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL6810353 | 0.75 | HDAC1 (0.46) | HDAC3HDAC1HDAC2NCOR2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | HDAC3 2501/4885HDAC1 1603/4885HDAC2 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.