Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207843 | 0.88 | MEN1 (0.45) | ATRPPARDMEN1KMT2ATAAR1 | |
| SCHEMBL6540512 | 0.85 | SCN9A (0.41) | PPARDSCN9ATAAR1PIK3CARCE1 | |
| SCHEMBL6277754 | 0.83 | PPARD (0.43) | PPARDSCN9AMEN1KMT2ATAAR1 | |
| SCHEMBL6540528 | 0.83 | ALDH1A1 (0.38) | PPARDSCN9AMEN1KMT2ATAAR1 | |
| SCHEMBL6325951 | 0.82 | PPARD (0.38) | ATRPPARDMEN1KMT2ATAAR1 | |
| SCHEMBL6539388 | 0.82 | PPARD (0.38) | ATRPPARDMEN1KMT2ATAAR1 | |
| SCHEMBL6234081 | 0.81 | PPARD (0.39) | ATRPPARDMEN1KMT2ATAAR1 | |
| SCHEMBL6539657 | 0.81 | PPARD (0.43) | ATRPPARDMEN1KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL6538837 | 0.80 | PPARD (0.42) | ATRPPARDMEN1KMT2ATAAR1 | |
| SCHEMBL6538764 | 0.80 | PPARD (0.39) | ATRPPARDMEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | ATR 4740/4885PPARD 1747/4885SCN9A 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.