Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540800 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6539551 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6539541 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6539973 | 0.93 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6540485 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6540945 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6540390 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6540397 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6540926 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTCYP1A2CYP2D6 | |
| SCHEMBL6539497 | 0.82 | TAS2R14 (0.44) | ALDH1A1TSHRKCNH2TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ALDH1A1 188/4885TSHR 3667/4885MAPT 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.