Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 5/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541525 | 0.92 | KCNH2 (0.41) | NR1H3ADRB3ADRB1KCNH2ALDH1A1 | |
| SCHEMBL6539972 | 0.91 | CA12 (0.48) | ADRB3ADRB1ADRB2CA12CA1 | |
| SCHEMBL6539982 | 0.91 | CA12 (0.48) | ADRB3ADRB1ADRB2CA12CA1 | |
| SCHEMBL6539979 | 0.91 | CA12 (0.48) | ADRB3ADRB1ADRB2CA12CA1 | |
| SCHEMBL6539497 | 0.90 | TAS2R14 (0.44) | NR1H3ADRB3KCNH2ALDH1A1TSHR | |
| SCHEMBL6540839 | 0.89 | NR1H3 (0.40) | NR1H3KCNH2ALDH1A1CA12CA1 | |
| SCHEMBL6679661 | 0.88 | KCNH2 (0.38) | NR1H3ADRB3ADRB1KCNH2ALDH1A1 | |
| SCHEMBL6679662 | 0.88 | KCNH2 (0.38) | NR1H3ADRB3ADRB1KCNH2ALDH1A1 | |
| SCHEMBL6800072 | 0.87 | ADRB1 (0.46) | NR1H3ADRB3ADRB1ADRB2CA12 | |
| SCHEMBL6800065 | 0.87 | ADRB1 (0.46) | NR1H3ADRB3ADRB1ADRB2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | NR1H3 598/4885ADRB3 58/4885ADRB1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.