Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL17422 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1526184 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL30145601 | 0.94 | — | — | |
| Bicarbonate SCHEMBL408952 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL11293716 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1491908 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31265062 | 0.89 | — | — | |
| Bicarbonate SCHEMBL15401807 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL12500507 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3446226 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016313-B1 | STABLE AQUEOUS COPPER ZIRCONIUM COMPLEX SALT SOLUTIONS, THEIR PREPARATION AND USE | MAGNESIUM ELEKTRON INC. (US) | 1982-09-22 | — | — | EP | claimed |
| US-4274972-A | Process for preparing dilute aqueous copper zirconium ammonium carbonate solutions containing less than about 0.5% Cu and 1.5% ZrO2 | MAGNESIUM ELEKTRON INC. (US) | 1981-06-23 | — | — | US | claimed |
| EP-0016313-A1 | Stable aqueous copper zirconium complex salt solutions, their preparation and use | MAGNESIUM ELEKTRON INC. (US) | 1980-10-01 | — | — | EP | claimed |
| US-4200672-A | Stable copper zirconium complex salt solutions for enhancing the resistance to rot of cotton fabrics | MAGNESIUM ELEKTRON INC. (US) | 1980-04-29 | — | — | US | claimed |
| EP-0877551-A4 | COMPOSITIONS AND METHODS FOR PRESERVING WOOD PRODUCTS | UNITED STATES BORAX INC (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-0877551-A1 | COMPOSITIONS AND METHODS FOR PRESERVING WOOD PRODUCTS | U.S. BORAX INC. (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997014303-A1 | COMPOSITIONS AND METHODS FOR PRESERVING WOOD PRODUCTS | U.S. BORAX INC. (US) | 1997-04-24 | — | — | WO | disclosed |
| US-5612094-A | IN SITU FORMATION OF ZIRCONIUM BORATE COMPLES | U.S. BORAX INC. (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0016313-B1 | STABLE AQUEOUS COPPER ZIRCONIUM COMPLEX SALT SOLUTIONS, THEIR PREPARATION AND USE | MAGNESIUM ELEKTRON INC. (US) | 1982-09-22 | — | — | EP | disclosed |
| US-4274972-A | Process for preparing dilute aqueous copper zirconium ammonium carbonate solutions containing less than about 0.5% Cu and 1.5% ZrO2 | MAGNESIUM ELEKTRON INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4274972-A | Process for preparing dilute aqueous copper zirconium ammonium carbonate solutions containing less than about 0.5% Cu and 1.5% ZrO2 | MAGNESIUM ELEKTRON INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4274972-A | Process for preparing dilute aqueous copper zirconium ammonium carbonate solutions containing less than about 0.5% Cu and 1.5% ZrO2 | MAGNESIUM ELEKTRON INC. (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0016313-A1 | Stable aqueous copper zirconium complex salt solutions, their preparation and use | MAGNESIUM ELEKTRON INC. (US) | 1980-10-01 | — | — | EP | disclosed |
| EP-0016313-A1 | Stable aqueous copper zirconium complex salt solutions, their preparation and use | MAGNESIUM ELEKTRON INC. (US) | 1980-10-01 | — | — | EP | disclosed |
| US-4200672-A | Stable copper zirconium complex salt solutions for enhancing the resistance to rot of cotton fabrics | MAGNESIUM ELEKTRON INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4200672-A | Stable copper zirconium complex salt solutions for enhancing the resistance to rot of cotton fabrics | MAGNESIUM ELEKTRON INC. (US) | 1980-04-29 | — | — | US | disclosed |