Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.66 |
| ▸ | TLR4 | O00206 | 4/20 | 0.59 |
| ▸ | TLR2 | O60603 | 4/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | VCP | P55072 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541530 | 1.00 | FBP1 (0.66) | FBP1TLR4TLR2NFE2L2VCP | |
| SCHEMBL6540500 | 0.91 | FBP1 (0.76) | FBP1TLR4TLR2VCPEGFR | |
| SCHEMBL6540497 | 0.91 | FBP1 (0.76) | FBP1TLR4TLR2VCPEGFR | |
| SCHEMBL6540241 | 0.87 | FBP1 (0.66) | FBP1TLR4TLR2NFE2L2VCP | |
| SCHEMBL6540237 | 0.87 | FBP1 (0.66) | FBP1TLR4TLR2NFE2L2VCP | |
| SCHEMBL6539480 | 0.86 | FBP1 (0.81) | FBP1TLR4TLR2NFE2L2VCP | |
| SCHEMBL6539482 | 0.86 | FBP1 (0.81) | FBP1TLR4TLR2NFE2L2VCP | |
| SCHEMBL278627 | 0.80 | FBP1 (1.00) | FBP1TLR4TLR2VCPTERT | |
| SCHEMBL792987 | 0.80 | FBP1 (1.00) | FBP1TLR4TLR2VCPTERT | |
| SCHEMBL8765211 | 0.80 | FBP1 (1.00) | FBP1TLR4TLR2VCPTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | FBP1 1286/4885TLR4 4195/4885TLR2 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.