Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 1.00 |
| ▸ | TLR4 | O00206 | 7/20 | 0.71 |
| ▸ | TLR2 | O60603 | 7/20 | 0.71 |
| ▸ | TERT | O14746 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | VCP | P55072 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765211 | 1.00 | FBP1 (1.00) | FBP1TLR4TLR2TERTMAOA | |
| SCHEMBL31287227 | 1.00 | FBP1 (1.00) | FBP1TLR4TLR2TERTMAOA | |
| SCHEMBL278627 | 1.00 | FBP1 (1.00) | FBP1TLR4TLR2TERTMAOA | |
| SCHEMBL6540500 | 0.87 | FBP1 (0.76) | FBP1TLR4TLR2TERTMAOA | |
| SCHEMBL6540497 | 0.87 | FBP1 (0.76) | FBP1TLR4TLR2TERTMAOA | |
| SCHEMBL6278181 | 0.83 | FBP1 (0.71) | FBP1TLR4TLR2 | |
| SCHEMBL334577 | 0.82 | FBP1 (0.70) | FBP1TLR4TLR2VCP | |
| SCHEMBL334578 | 0.82 | FBP1 (0.70) | FBP1TLR4TLR2VCP | |
| SCHEMBL510714 | 0.82 | TLR4 (1.00) | FBP1TLR4TLR2TERTMAOA | |
| SCHEMBL510715 | 0.82 | TLR4 (1.00) | FBP1TLR4TLR2TERTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277072-B | A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives | JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| EP-2982368-A1 | Small molecule compounds displacing focal adhesion core components | Universität Konstanz (DE) | 2016-02-10 | — | — | EP | claimed |
| CN-104277072-A | Method for preparing (E)-2-aryl vinyl phosphonate derivatives | CHINASUN SPECIALTY PRODUCTS CO LTD | 2015-01-14 | — | — | CN | claimed |
| CN-107188771-B | Chiral synthesis method of gamma-nitrophenol compound | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020212697-A1 | INHIBITOR COMPOUNDS | Azeria Therapeutics Limited (GB) | 2020-10-22 | — | — | WO | disclosed |
| US-9956191-B2 | Composition of 5-nitrobenzoate derivatives as anti-metastatic agent that inhibits tumor cell-induced platelet aggregation | UNIV CHANG GUNG (TW) | 2018-05-01 | — | — | US | disclosed |
| CN-107827774-A | Nitrosamine compound containing two fluoro ethyls and preparation method thereof | 遵义医学院 | 2018-03-23 | — | — | CN | disclosed |
| US-20170172949-A1 | COMPOSITION OF 5-NITROBENZOATE DERIVATIVES AS ANTI-METASTATIC AGENT THAT INHIBITS TUMOR CELL-INDUCED PLATELET AGGREGATION | CHANG GUNG UNIVERSITY (TW) | 2017-06-22 | — | — | US | disclosed |
| US-9604910-B2 | Composition of 5-nitrobenzoate derivatives as anti-metastatic agent that inhibits tumor cell-induced platelet aggregation | CHANG GUNG UNIVERSITY (TW) | 2017-03-28 | — | — | US | disclosed |
| CN-104277072-B | A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives | JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) | 2016-04-13 | — | — | CN | disclosed |
| EP-2982368-A1 | Small molecule compounds displacing focal adhesion core components | Universität Konstanz (DE) | 2016-02-10 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |
| EP-0513174-A1 | 4,5-CYCLOALKANO-3-BENZAZEPIN-7-OL-DERIVATIVES AND THEIR USE. | SCHERING CORP (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992018475-A2 | SUBSTITUTED PHENYLAZACYCLOALKANES AS CNS AGENTS | THE UPJOHN COMPANY (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1991011437-A1 | 4,5-CYCLOALKANO-3-BENZAZEPIN-7-OL-DERIVATIVES AND THEIR USE | SCHERING CORPORATION (US) | 1991-08-08 | — | — | WO | disclosed |
| US-4820734-A | ANALGESICS,ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0138030-B1 | PHENYLETHYLAMINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-09-30 | — | — | EP | disclosed |
| EP-0138030-A2 | Phenylethylamine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-04-24 | — | — | EP | disclosed |
| EP-0028959-B1 | 5,8,13,13A-TETRAHYDRO-6H-DIBENZO(A,G)QUINOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | U.R.P.H.A. (FR) | 1985-01-30 | — | — | EP | disclosed |
| EP-0028959-A1 | 5,8,13,13a-Tetrahydro-6H-dibenzo(a,g)quinolizine derivatives, process for their preparation and pharmaceutical compositions containing them | U.R.P.H.A. (FR) | 1981-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172949-A1 | COMPOSITION OF 5-NITROBENZOATE DERIVATIVES AS ANTI-METASTATIC AGENT THAT INHIBITS TUMOR CELL-INDUCED PLATELET AGGREGATION | PTAFR, PF4, F11 | FBP1 2532/4885TLR4 3428/4885TLR2 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.