Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.74 |
| ▸ | MEN1 | O00255 | 10/20 | 0.74 |
| ▸ | NPC1 | O15118 | 9/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.74 |
| ▸ | POLB | P06746 | 7/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | RECQL | P46063 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | APEX1 | P27695 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541745 | 1.00 | KMT2A (0.74) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL13854024 | 0.90 | KMT2A (0.74) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL4024692 | 0.85 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL4024688 | 0.85 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6037177 | 0.82 | KMT2A (0.66) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6037174 | 0.82 | KMT2A (0.66) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL31530568 | 0.75 | RAB9A (0.77) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL31530581 | 0.75 | RAB9A (0.77) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10981054 | 0.74 | ALDH1A1 (1.00) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL8290592 | 0.74 | KMT2A (0.76) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477475-A1 | Compounds for use as a medicine increasing the contractility of a heart, a heart muscle or cells of a heart muscle | Procorde GmbH (DE) | 2004-11-17 | — | — | EP | disclosed |