Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TKT | P29401 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nimustine SCHEMBL23301409 | 0.83 | BLM (1.00) | LMNANFKB1BLMPMP22CYP1A2 | |
| Nimustine SCHEMBL8414 | 0.83 | BLM (1.00) | LMNANFKB1BLMPMP22CYP1A2 | |
| Nimustine SCHEMBL98303 | 0.82 | BLM (0.98) | LMNANFKB1BLMPMP22CYP1A2 | |
| Nimustine SCHEMBL124427 | 0.82 | BLM (0.98) | LMNANFKB1BLMPMP22CYP1A2 | |
| Nimustine SCHEMBL1649545 | 0.82 | BLM (0.98) | LMNANFKB1BLMPMP22CYP1A2 | |
| Nimustine SCHEMBL1649348 | 0.81 | BLM (0.96) | LMNANFKB1BLMPMP22CYP1A2 | |
| SCHEMBL25299723 | 0.81 | LMNA (0.79) | LMNANFKB1BLMPMP22TKT | |
| Nimustine SCHEMBL1580335 | 0.79 | BLM (0.92) | LMNANFKB1BLMPMP22CYP1A2 | |
| SCHEMBL15534393 | 0.79 | LMNA (0.59) | LMNANFKB1BLMPMP22ALDH1A1 | |
| SCHEMBL29594139 | 0.78 | LMNA (0.57) | LMNANFKB1BLMPMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408909-A4 | IMPROVED CONDITIONALLY REPLICATING VECTORS FOR INHIBITING VIRAL INFECTIONS | VIRXSYS CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1408909-A2 | IMPROVED CONDITIONALLY REPLICATING VECTORS FOR INHIBITING VIRAL INFECTIONS | VIRxSYS Corporation (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-1356070-A2 | CONDITIONALLY REPLICATING VIRAL VECTORS AND THEIR USE | Virxsys (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002024897-A9 | CONDITIONALLY REPLICATING VIRAL VECTORS AND THEIR USE | VIRXSYS (US) | 2003-03-20 | — | — | WO | disclosed |
| US-20030026791-A1 | Conditionally replicating vectors for inhibiting viral infections | VIRXSYS CORPORATION | 2003-02-06 | — | — | US | disclosed |
| WO-2002078631-A2 | IMPROVED CONDITIONALLY REPLICATING VECTORS FOR INHIBITING VIRAL INFECTIONS | VIRXSYS (US) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002024897-A2 | CONDITIONALLY REPLICATING VIRAL VECTORS AND THEIR USE | VIRXSYS (US) | 2002-03-28 | — | — | WO | disclosed |