Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542021 | 0.88 | MAPT (0.40) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6542220 | 0.86 | EDNRA (0.48) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6542752 | 0.82 | EDNRA (0.49) | MAPTKDM4EALDH1A1POLBHTT | |
| SCHEMBL6541879 | 0.80 | EDNRA (0.41) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6541894 | 0.78 | ELANE (0.38) | MAPTPOLBCA12CA9RAB9A | |
| SCHEMBL6542606 | 0.74 | EDNRA (0.43) | MAPTKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6542075 | 0.74 | EDNRA (0.49) | MAPTPOLBHPGDCA12CA1 | |
| SCHEMBL6542684 | 0.74 | EDNRA (0.42) | MAPTKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6542017 | 0.73 | EDNRA (0.47) | MAPTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6541388 | 0.73 | EDNRA (0.43) | MAPTKDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009743-B1 | CERTAIN BENZOTHIAZINE DIOXIDE ENDOTHELIN ANTAGONISTS AND PROCESSES FOR THEIR PREPARATION | WARNER LAMBERT CO (US) | 2004-06-30 | — | — | EP | claimed |