Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542157 | 1.00 | MEN1 (0.48) | MEN1KMT2ANR1H4ADRB1ADRB3 | |
| SCHEMBL7533753 | 0.87 | SLC16A3 (0.43) | MEN1KMT2ABACE1POLB | |
| SCHEMBL6538563 | 0.87 | ADRB1 (0.54) | MEN1KMT2AADRB1ADRB3NPC1 | |
| SCHEMBL6538597 | 0.85 | NR1H4 (0.48) | MEN1KMT2ANR1H4ADRB1ADRB3 | |
| SCHEMBL6538732 | 0.85 | ADRB1 (0.50) | MEN1KMT2AADRB1ADRB3NPC1 | |
| SCHEMBL6538833 | 0.85 | ADRB3 (0.61) | MEN1KMT2AADRB1ADRB3NPC1 | |
| SCHEMBL6540060 | 0.83 | ADRB1 (0.48) | MEN1KMT2AADRB1ADRB3NPC1 | |
| SCHEMBL6538663 | 0.83 | ADRB1 (0.48) | MEN1KMT2AADRB1ADRB3NPC1 | |
| SCHEMBL6539512 | 0.82 | ADRB1 (0.52) | MEN1KMT2AADRB1ADRB3NPC1 | |
| SCHEMBL6539030 | 0.82 | KDM4E (0.47) | MEN1KMT2AADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |