Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542153 | 0.87 | MEN1 (0.48) | BACE1MEN1KMT2APOLB | |
| SCHEMBL6542157 | 0.87 | MEN1 (0.48) | BACE1MEN1KMT2APOLB | |
| SCHEMBL6538563 | 0.75 | ADRB1 (0.54) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6538732 | 0.74 | ADRB1 (0.50) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6538833 | 0.73 | ADRB3 (0.61) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL6538597 | 0.73 | NR1H4 (0.48) | MEN1KMT2A | |
| SCHEMBL6540060 | 0.72 | ADRB1 (0.48) | MEN1KMT2APOLB | |
| SCHEMBL6538663 | 0.72 | ADRB1 (0.48) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7037437 | 0.71 | ALDH1A1 (0.52) | MAPTABCB1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6539058 | 0.71 | ADRB1 (0.45) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |