Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52259 | 0.78 | — | — | |
| Tetrafluoroethylene SCHEMBL6342942 | 0.64 | — | — | |
| SCHEMBL607360 | 0.63 | — | — | |
| Bromide SCHEMBL1558920 | 0.62 | — | — | |
| SCHEMBL9473570 | 0.61 | — | — | |
| SCHEMBL25066901 | 0.61 | — | — | |
| SCHEMBL30094258 | 0.61 | — | — | |
| SCHEMBL30094248 | 0.61 | — | — | |
| SCHEMBL3385002 | 0.61 | — | — | |
| SCHEMBL799025 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |