Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921 | 0.99 | MEN1 (0.42) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL9026507 | 0.98 | MEN1 (0.41) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL4280650 | 0.98 | MEN1 (0.41) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL8557974 | 0.98 | MEN1 (0.41) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL10516186 | 0.87 | MEN1 (0.43) | MEN1KMT2AHTTTDP1KDM4E | |
| SCHEMBL8467232 | 0.87 | NOS3 (0.40) | HTTKDM4ENPSR1RAB9ANPC1 | |
| SCHEMBL8817089 | 0.84 | KDM4E (0.42) | MEN1KMT2AHTTTDP1KDM4E | |
| Masoprocol SCHEMBL6246633 | 0.84 | KMT2A (0.37) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL7894146 | 0.84 | AADAT (0.34) | MEN1KMT2A | |
| SCHEMBL9212414 | 0.83 | HTT (0.40) | MEN1KMT2AHTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223809-A4 | METHODS OF TREATING HAIR LOSS COMPRISING ADMINISTERING INDOLINE COMPOUND | UNIV TEXAS SOUTHWESTERN MED CT (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223809-A1 | METHODS OF TREATING HAIR LOSS COMPRISING ADMINISTERING INDOLINE COMPOUND | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030151-A1 | METHODS OF TREATING HAIR LOSS COMPRISING ADMINISTERING INDOLINE COMPOUND | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2001-05-03 | — | — | WO | disclosed |
| US-5968969-A | BENZATHINE AND LIDOCAINE SALTS OF SELECTED CARBOXAMIDES FOR INTRA-ARTICULAR INJECTION | PFIZER INC (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0826685-A1 | Stable, long acting salts of carboxamides for the treatment of joint disease | PFIZER INC. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1997022605-A1 | STABLE, LONG ACTING SALTS OF INDOLE DERIVATIVES FOR THE TREATMENT OF JOINT DISEASES | PFIZER INC. (US) | 1997-06-26 | — | — | WO | disclosed |