SCHEMBL6542299

SCHEMBL6542299

CCCCn1c(O)cc(C)c(NC=O)c1=O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 12/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CNR1 P21554 2/20 0.37
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TYR P14679 1/20 0.36
ADRA2A P08913 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401780 0.85 MEN1 (0.41) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL7580760 0.85 CNR2 (0.40) CNR2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL9401793 0.85 KDM4E (0.39) ALDH1A1KDM4ESMN1; SMN2LMNAHPGD
SCHEMBL4650114 0.84 LMNA (0.30) LMNA
SCHEMBL11824942 0.82 KDM4E (0.46) CNR2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL11235843 0.79 TDP1 (0.42) CNR2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL9401958 0.77 TTR (0.31)
SCHEMBL11295145 0.76 CNR2 (0.43) CNR2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL11241641 0.76 ALDH1A1 (0.46) CNR2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL11290276 0.75 ALDH1A1 (0.49) CNR2ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1218449-B1 MONOAZO DYESTUFFS USEFUL FOR COLOUR FILTERS AND INK JET PRINTING AVECIA LTD (GB) 2004-07-14 EP disclosed
US-6723835-B1 PRINTING DYE; COLOR FILTER; YELLOW; CARBOXY GROUPS ORTHO TO THE AZO LINKAGE PROVIDE LIGHTFASTNESS VERSUS RELATED ORTHO-SULPHO ANALOGUES, WITH NO LOSS IN BRIGHTNESS AVECIA LIMITED (GB) 2004-04-20 US disclosed