Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726615 | 0.91 | — | — | |
| SCHEMBL9398462 | 0.80 | S1PR2 (0.48) | LMNABLM | |
| SCHEMBL676903 | 0.77 | OPRM1 (0.46) | LMNABLM | |
| SCHEMBL28089322 | 0.77 | CA12 (0.36) | GSRCA12CA1CA2CA3 | |
| SCHEMBL28575182 | 0.77 | CA12 (0.36) | GSRCA12CA1CA2CA3 | |
| SCHEMBL9474735 | 0.77 | CA12 (0.36) | GSRCA12CA1CA2CA3 | |
| SCHEMBL18838779 | 0.77 | CA12 (0.36) | GSRCA12CA1CA2CA3 | |
| SCHEMBL16696692 | 0.77 | DNM1 (0.53) | GSRCA12CA1CA2CA3 | |
| SCHEMBL351453 | 0.77 | DNM1 (0.53) | GSRCA12CA1CA2CA3 | |
| SCHEMBL350445 | 0.77 | DNM1 (0.53) | GSRCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421386-A4 | HIGH CAPACITY ASSAY PLATFORMS | SIGMA ALDRICH CO (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1421386-A2 | HIGH CAPACITY ASSAY PLATFORMS | Sigma-Aldrich Company (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2002092834-A2 | HIGH CAPACITY ASSAY PLATFORMS | SIGMA-ALDRICH CO. (US) | 2002-11-21 | — | — | WO | disclosed |