Isoflavone

Isoflavone

SCHEMBL6542422

O=c1c(-c2ccccc2)coc2ccccc12.O=c1c(-c2ccccc2)coc2ccccc12.O=c1c(-c2ccccc2)coc2ccccc12

nearest known ligand 0.66

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.66
SMN1; SMN2 Q16637 7/20 0.66
NPC1 O15118 6/20 0.66
RAB9A P51151 6/20 0.66
KDM4E B2RXH2 4/20 0.66
POLB P06746 2/20 0.66
NPSR1 Q6W5P4 1/20 0.66
MIF P14174 1/20 0.64
MAPT P10636 6/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
TP53 P04637 4/20 0.60
CYP3A4 P08684 3/20 0.60
HPGD P15428 3/20 0.60
MAOB P27338 6/20 0.58
HDAC6 Q9UBN7 2/20 0.56
MAPK1 P28482 2/20 0.56
GAA P10253 1/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoflavone SCHEMBL8028 1.00 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL31264756 1.00 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL6290885 1.00 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27846670 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27553920 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL5846515 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL5854324 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27768861 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL5846511 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27590547 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1303187-A4 PROCESS FOR OBTAINING SOLID SOY ISOFLAVONE-CONTAINING PRODUCTS SOLBAR PLANT EXTRACTS AGRICULT (IL) 2004-10-06 EP disclosed
EP-1303187-A2 PROCESS FOR OBTAINING SOLID SOY ISOFLAVONE-CONTAINING PRODUCTS Solbar Plant Extracts, Agricultural Co-Operative Society Ltd (IL) 2003-04-23 EP disclosed
WO-2002056700-A2 PROCESS FOR OBTAINING SOLID SOY ISOFLAVONE-CONTAINING PRODUCTS SOLBAR PLANT EXTRACTS, AGRICULTURAL CO-OPERATIVE SOCIETY LTD. (IL) 2002-07-25 WO disclosed