Isoflavone

Isoflavone

SCHEMBL8028

O=c1c(-c2ccccc2)coc2ccccc12

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.66
SMN1; SMN2 Q16637 7/20 0.66
NPC1 O15118 6/20 0.66
RAB9A P51151 6/20 0.66
KDM4E B2RXH2 4/20 0.66
POLB P06746 2/20 0.66
NPSR1 Q6W5P4 1/20 0.66
MIF P14174 1/20 0.64
MAPT P10636 6/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
TP53 P04637 4/20 0.60
CYP3A4 P08684 3/20 0.60
HPGD P15428 3/20 0.60
MAOB P27338 6/20 0.58
HDAC6 Q9UBN7 2/20 0.56
MAPK1 P28482 2/20 0.56
GAA P10253 1/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoflavone SCHEMBL31264756 1.00 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL6542422 1.00 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL6290885 1.00 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27846670 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27553920 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL5846515 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL5854324 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27768861 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL5846511 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
Isoflavone SCHEMBL27590547 0.98 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 61111 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121378801-B Photo-crosslinking double-network hydrogel for promoting skin wound healing and preparation method thereof Shandong second people's Hospital (Shandong ear nose throat hospital, Shandong ear nose throat Research Institute) (CN) 2026-05-26 CN claimed
CN-121081509-B Exosome preparation for treating thin endometrium and preparation method thereof ANHUI KEMEN BIOTECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075471-A Isoflavone type use of compounds 2026-05-26 CN claimed
CN-122075533-A S-equol composition for delaying ovarian aging and application thereof 2026-05-26 CN claimed
WO-2026103350-A1 ANTI-TUMOR AND/OR ANTI-FERROPTOSIS SMALL MOLECULE COMPOSITION AND USE THEREOF 北京慧宝源生物技术股份有限公司 2026-05-21 WO claimed
US-20260137715-A1 AQUEOUS FORMULATION INCLUDING DISSOLVED HYDROGEN GAS AND MINERALS AND ADDITIVES BEST PLANET SCIENCE LLC (US) 2026-05-21 US claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122036668-A Alpha, beta unsaturated ketone substituted chromone derivative and medicinal use thereof 中国药科大学 2026-05-15 CN claimed
CN-122004591-A Cosmetic powder pen and preparation method thereof 上海星妤生物科技有限公司 2026-05-12 CN claimed
WO-1991001724-A1 RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION G.D. SEARLE & CO. (US) 1991-02-21 WO claimed
US-4960908-A ANTIBODY INHIBITOR AND ANTICARCINOGENIC AGENT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1990-10-02 US claimed
US-4841077-A Isoflavone derivatives, and salts thereof, and cancerocidal and immunosuppressive agents containing the same YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1989-06-20 US claimed
EP-0245518-A1 ISOFLAVONE DERIVATIVES, SALTS THEREOF, AND ONCOSTATIC AND IMMUNOSUPPRESSIVE AGENTS YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1987-11-19 EP claimed
EP-0129893-A2 Ground mixture Takeda Chemical Industries, Ltd. (JP) 1985-01-02 EP claimed
EP-0124393-A1 Hair dyeing composition and process ALBAN MULLER INTERNATIONAL, S.A.R.L. (FR) 1984-11-07 EP claimed
EP-0025783-A4 A PHARMACEUTICAL COMPOSITION FOR USE IN REDUCING SERUM CHOLESTEROL LEVELS. Z L LTD PARTNERSHIP (US) 1981-10-27 EP claimed
EP-0025783-A1 A PHARMACEUTICAL COMPOSITION FOR USE IN REDUCING SERUM CHOLESTEROL LEVELS Z-L LIMITED PARTNERSHIP (US) 1981-04-01 EP claimed
US-4234577-A ANTICHOLESTEROL AGENTS, OXIDATION RESISTANCE Z-L LIMITED PARTNERSHIP (US) 1980-11-18 US claimed
WO-1980002027-A1 ERGOSTADIENTRIOLS,COMPOSITIONS CONTAINING SAME,AND METHODS OF PREPARING AND USING SAME Z L PARTNERSHIP LTD (US) 1980-10-02 WO claimed