Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542521 | 1.00 | MASP2 (0.71) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL560440 | 0.84 | MASP2 (1.00) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL560439 | 0.84 | MASP2 (1.00) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL10309054 | 0.74 | MASP2 (0.72) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL11701260 | 0.73 | MASP2 (0.77) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL11701268 | 0.73 | MASP2 (0.77) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL2561722 | 0.73 | HCAR2 (1.00) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL125126 | 0.73 | HCAR2 (1.00) | MASP2F2HCAR2POLBALDH1A1 | |
| SCHEMBL125125 | 0.73 | HCAR2 (1.00) | MASP2F2HCAR2POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL6744115 | 0.71 | HCAR2 (0.96) | MASP2F2HCAR2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408946-A4 | HISTONE DEACETYLASE INHIBITORS | CIRCAGEN PHARMACEUTICAL (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1408946-A2 | HISTONE DEACETYLASE INHIBITORS | Circagen Pharmaceutical (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002076941-A2 | HISTONE DEACETYLASE INHIBITORS | CIRCAGEN PHARMACEUTICAL (US) | 2002-10-03 | — | — | WO | disclosed |