Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.56 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.56 |
| ▸ | CACNA1B known ✓ | Q00975 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.96 |
| ▸ | MASP2 | O00187 | 1/20 | 0.73 |
| ▸ | F2 | P00734 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | POLB | P06746 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561722 | 0.98 | HCAR2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL125125 | 0.98 | HCAR2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL125126 | 0.98 | HCAR2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL10857031 | 0.88 | HCAR2 (0.80) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL9222011 | 0.85 | HCAR2 (0.75) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL9222017 | 0.85 | HCAR2 (0.75) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL560440 | 0.85 | MASP2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL560439 | 0.85 | MASP2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| Di(Hydroxyethyl)Ether SCHEMBL28902252 | 0.84 | HCAR2 (0.73) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL979497 | 0.83 | HCAR2 (0.74) | HCAR2MASP2F2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204292-B1 | PROCESS FOR THE PRODUCTION OF PRINTED CIRCUITS USING A PHOTOPOLYMERISABLE SYSTEM | SIEMENS AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | claimed |
| US-4920038-A | Printed circuit manufacture employing a radiation cross-linkable photo-polymer system | SIEMENS AKTIENGESELLSCHAFT | 1990-04-24 | — | — | US | claimed |
| EP-0167051-B1 | THERMOSTABLE AND IRRADIATION-CURABLE POLYMER SYSTEM BASED ON BISPHENOL AND EPICHLOROHYDRINE, AND METHOD FOR ITS PREPARATION | SIEMENS AKTIENGESELLSCHAFT (DE) | 1988-10-12 | — | — | EP | claimed |
| CN-103467567-B | Chemical synthesis method for furan allyl fluorescent dipeptide metalloproteinase substrate | UNIV JIANGXI NORMAL SCI & TECH | 2015-03-04 | — | — | CN | disclosed |
| CN-103467567-A | Chemical synthesis method for furan allyl fluorescent dipeptide metalloproteinases substrate | UNIV JIANGXI NORMAL SCI & TECH | 2013-12-25 | — | — | CN | disclosed |
| US-6696114-B1 | POLARIZED ULTRAVIOLET RADIATED HYDROCARBON, (METH)ACRYLATE, OR SILOXANE POLYMER | HAYASHI TELEMPU CO., LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| US-4920038-A | Printed circuit manufacture employing a radiation cross-linkable photo-polymer system | SIEMENS AKTIENGESELLSCHAFT | 1990-04-24 | — | — | US | disclosed |
| US-4610983-A | N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| US-4356247-A | LITHOGRAPHY; PRINTING PLATES; PHOTORESISTS; HIGH-SPEED SENSITIZERS; SOTRAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1982-10-26 | — | — | US | disclosed |